Reviewed by PeptideGuide Research Team|Last updated February 15, 2026
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GHK vs Matrixyl (Palmitoyl Pentapeptide-4)
Complete side-by-side comparison of GHK and Matrixyl (Palmitoyl Pentapeptide-4).
Side-by-Side Comparison
Property
GHK
Matrixyl (Palmitoyl Pentapeptide-4)
Name
GHK
Matrixyl (Palmitoyl Pentapeptide-4)
Peptide Class
Signal peptide
Cosmetic Peptide
Category
Recovery and Repair
Skin and Cosmetic
Dosage Range
N/A
N/A
Half-Life
N/A
N/A
FDA Status
Not Approved
Not FDA approved for medical use
Safety Rating
Generally Well-Tolerated
Generally Well-Tolerated
Cost Estimate
$50-100 per month
$30-60 per month
GHK
GHK, or Glycyl-L-histidyl-L-lysine, is a naturally occurring tripeptide with significant roles in skin regeneration and wound healing. Known for its a...
View full profile →Matrixyl (Palmitoyl Pentapeptide-4)
Matrixyl, also known as Palmitoyl Pentapeptide-4, is a cosmetic peptide primarily used in anti-aging skincare products. It is renowned for its ability...
View full profile →