Reviewed by PeptideGuide Research Team|Last updated February 15, 2026
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Orexin A (Hypocretin-1) vs Orexin B (Hypocretin-2)
Complete side-by-side comparison of Orexin A (Hypocretin-1) and Orexin B (Hypocretin-2).
Side-by-Side Comparison
Property
Orexin A (Hypocretin-1)
Orexin B (Hypocretin-2)
Name
Orexin A (Hypocretin-1)
Orexin B (Hypocretin-2)
Peptide Class
Neuropeptide
Neuropeptide
Category
Neuropeptide
Neuropeptide
Dosage Range
N/A
N/A
Half-Life
N/A
N/A
FDA Status
Not Approved
Not Approved
Safety Rating
Research Only
Not Established
Cost Estimate
N/A
N/A
Orexin A (Hypocretin-1)
Orexin A, also known as Hypocretin-1, is a neuropeptide that plays a significant role in the regulation of wakefulness and appetite. It operates by bi...
View full profile →Orexin B (Hypocretin-2)
Orexin B, also known as Hypocretin-2, is a neuropeptide involved in the regulation of arousal, wakefulness, and appetite. It primarily interacts with ...
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