Reviewed by PeptideGuide Research TeamLast updated February 15, 2026

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Semaglutide vs Liraglutide

Complete side-by-side comparison of Semaglutide and Liraglutide.

Side-by-Side Comparison

Property
Semaglutide
Liraglutide
Name
Semaglutide
Liraglutide
Peptide Class
Glucagon-like peptide-1 (GLP-1) receptor agonist
GLP-1 receptor agonist
Category
Weight Loss and Metabolic
Weight Loss and Metabolic
Dosage Range
0.25 mg to 2.4 mg weekly
0.6 mg to 3 mg daily
Half-Life
Approximately 7 days
13 hours
FDA Status
Approved for Type 2 Diabetes and Weight Management
Approved
Safety Rating
Prescription Required
Prescription Required
Cost Estimate
$800-1200/month
$800-1200/month