Reviewed by PeptideGuide Research Team|Last updated February 15, 2026
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Tirzepatide vs Liraglutide
Complete side-by-side comparison of Tirzepatide and Liraglutide.
Side-by-Side Comparison
Property
Tirzepatide
Liraglutide
Name
Tirzepatide
Liraglutide
Peptide Class
Dual GIP and GLP-1 receptor agonist
GLP-1 receptor agonist
Category
Weight Loss and Metabolic
Weight Loss and Metabolic
Dosage Range
5 mg to 15 mg once weekly
0.6 mg to 3 mg daily
Half-Life
5 days
13 hours
FDA Status
Approved
Approved
Safety Rating
Prescription Required
Prescription Required
Cost Estimate
$500-800 per cycle
$800-1200/month
Tirzepatide
Tirzepatide is a novel dual agonist peptide that targets both the GIP and GLP-1 receptors, offering a unique approach to managing obesity and type 2 d...
View full profile →Liraglutide
Liraglutide is a GLP-1 receptor agonist primarily used for weight management and Type 2 diabetes control. It mimics the action of the GLP-1 hormone, e...
View full profile →